Fig. 2From: Induction of action-at-a-distance mutagenesis by 8-oxo-7,8-dihydroguanine in DNA pol λ-knockdown cellsEffects of the DNA pol λ knockdown in U2OS cells on the mutant frequency induced by GO:C. Open columns, control plasmid containing G:C at position 122; closed columns, plasmid containing GO:C at position 122. Transfection experiments were performed three (G:C) and four (GO:C) times. Data are expressed as the means + standard errors. *P < 0.05 vs. control siRNABack to article page