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Table 1 Mutations detected in the supF genea

From: Induction of action-at-a-distance mutagenesis by 8-oxo-7,8-dihydroguanine in DNA pol λ-knockdown cells

G : C
control   si-pol λ  
74A- > G 1 91G- > A 1
95C- > G 2 91G- > C 1
98A- > G 1 95C- > G 1
101C- > A 1 96 T- > G 1
117C- > T 3 101C- > T 1
120A- > G 1 101C- > A 2
121G- > T 1 108C- > T 1
130C- > T 1 117C- > T 1
large deletion 9 118G- > A 2
   119A- > Δ 1
   125C- > T 1
   126G- > T 1
   large insertion 1
   large deletion 4
total colonies analyzed 20 total colonies analyzed 19
GO : C
control   si-pol λ  
27G- > A 1 61G- > A 2
61G- > A, 95C- > G, 111C- > T, 130C- > A, 153C- > T 1 61G- > A, 130C- > A 2
67G- > A 2 61G- > A, 153C- > T 1
72C- > G 1 71C- > G 3
85G- > T 3 86G- > A 1
91G- > C 1 86G- > A, 112G- > A, 126G- > C 2
95C- > T, 122G- > T, 125C- > G 1 91G- > A, 122G- > T 1
95C- > G 1 91G- > C 2
101C- > G 1 95C- > G 2
107 T- > G, 122G- > T 1 95C- > G, 111C- > T 1
112G- > T 1 101C- > T, 122G- > T 1
118G- > C 4 111C- > T, 153C- > T 2
118G- > C, 123 T- > G 1 118G- > A 2
121G- > T 5 118G- > C 5
122G- > T 36 121G- > A 3
123 T- > G 2 121G- > T 2
130C- > T 2 122G- > A 3
large deletion 4 122G- > T 29
   122G- > C 2
   126G- > C 2
   130C- > A 1
   large deletion 5
total colonies analyzed 68 total colonies analyzed 74
  1. The numbers of colonies are shown on the right side
  2. aMutations detected in single colonies are represented. The sequence of the upper strand is shown