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Table 2 Spectra of mutations detected in the supF gene

From: Induction of action-at-a-distance mutagenesis by 8-oxo-7,8-dihydroguanine in DNA pol λ-knockdown cells

  G : C GO : C
  Control si-pol λ Control si-pol λ
mutations at position 122     
 G : C - > A : T 0 (0) 0 (0) 0 (0) 3 (4)
 G : C - > T : A 0 (0) 0 (0) 38 (56) 31 (42)
 G : C - > C : G 0 (0) 0 (0) 0 (0) 2 (3)
mutations at other positions     
 transition     
  A : T - > G : C 3 (15) 0 (0) 0 (0) 0 (0)
  G : C - > A : T 4 (20) 7 (37) 9 (13) 23 (31)
 transversion     
  A : T - > T : A 0 (0) 0 (0) 0 (0) 0 (0)
  A : T - > C : G 0 (0) 1 (5) 4 (6) 0 (0)
  G : C - > T : A 2 (10) 3 (16) 10 (15) 5 (7)
  G : C - > C : G 2 (10) 2 (11) 11 (16) 17 (23)
 small insertion (1–2 bp) 0 (0) 0 (0) 0 (0) 0 (0)
 large insertion (>2 bp) 0 (0) 1 (5) 0 (0) 0 (0)
 small deletion (1–2 bp) 0 (0) 1 (5) 0 (0) 0 (0)
 large deletion (>2 bp) 9 (45) 4 (21) 4 (6) 5 (7)
 others 0 (0) 0 (0) 0 (0) 0 (0)
total mutations 20 19 76 86
total colonies analyzed 20 (100) 19 (100) 68 (100) 74 (100)
  1. All data are represented as cases found (%)