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Fig. 3 | Genes and Environment

Fig. 3

From: Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue

Fig. 3

Expression and methylation across rs7164030 genotype in BrainCloud and MuTHER. The major “A” allele of rs7164030 was significantly and consistently associated with lower CHRNA5 mRNA expression in the BrainCloud (a) and MuTHER (b) datasets. The “A” allele was also associated with lower CpG methylation measured at two different probes (cg22563815 and cg17108064) in the BrainCloud prefrontal cortex (c and e) and the MuTHER adipose tissue (d and f)

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Genes and Environment

ISSN: 1880-7062

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