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Table 1 Frequency of micronucleus (MN) in mice bone marrow PCEs cells and PCE/NCE ratio induced by arsenic and sadagura alone and in combination

From: Arsenic and smokeless tobacco induce genotoxicity, sperm abnormality as well as oxidative stress in mice in vivo

Treatment groups Total PCE /n % PCE with MN (mean ± S.E) Total NCE PCE/NCE (mean ± S.E)
CON 12000/6 0.06 ± 0.03 5098 2.39 ± 0.13
SA1 12000/6 0.23 ± 0.04a* 5044 2.40 ± 0.11
SA2 12000/6 0.43 ± 0.04a*** 5160 2.34 ± 0.10c
SG 12000/6 0.22 ± 0.02b* 4760 2.52 ± 0.06d
SA1 + SG 12000/6 0.33 ± 0.01*** 5334 2.26 ± 0.06
SA2 + SG 12000/6 0.45 ± 0.02b*** 6625 1.86 ± 0.13cd*
  1. Description of treatment groups is given in methodology section. PCE Polychromatic erythrocyte, NCE Normochromatic erythrocyte. Statistical analysis: ANOVA. Groups bearing the same superscript are significantly different from each other: a, b = p < 0.001; d = p < 0.01; c = p < 0.05. Values are significantly different from control: * = p < 0.05; ** = p < 0.01; *** = p < 0.001
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Genes and Environment

ISSN: 1880-7062

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