Fig. 2From: Mechanisms of interstrand DNA crosslink repair and human disordersUHRF1-dependent recruitment of structure-specific endonucleases to ICLs. UHRF-1 is involved in the recruitment of FANCD2 and other DNA repair factors including XPF-ERCC1 and MUS81-EME1. Detailed mechanisms how UHRF1 recruits ICL repair factors are unclearBack to article page