Fig. 1

The effect of Cu(II) on mutagenic activity in Salmonella typhimurium TA100. Revertant colonies induced by: (a) 4NQO (0.02 μg/plate), 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (AF-2; 0.002 μg/plate), and quercetin (50 μg/plate) without S9 mix; (b) 2-aminoanthracene (2-AA; 0.2 μg/plate), benzo[a]pyrene (B[a]P; 0.5 μg/plate), and 3-amino-1,4-dimethyl-5H-pyrido-[4,3-b]indole (Trp-p-1; 0.1 μg/plate) with S9 mix. The concentration of Cu(II) solution tested is shown in parentheses. Values represent the mean ± standard deviation (n = 3). ^*Significant increase as determined using Welch’s t-test (P < 0.05). “†” indicates cytotoxicity