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Table 1 In vivo effect of arguta-juice in the diet on DNA adduct formation in liver of mice fed with 0.005 % MeIQx

From: Inhibitory effect of Actinidia arguta on mutagenesis, inflammation and two-stage mouse skin tumorigenesis

Group

No. of mice

MeIQx

Arguta-juice added to diet

Liver weight (g)

Adducts/ 108 nucleotide

1

8

0.005 %

Water

0.81 ± 0.039

44.9 ± 39.5

2

8

0.005 %

arguta-juice (x1)

0.86 ± 0.075

35.9 ± 39.0

3

8

0.005 %

arguta-juice (x3)

0.87 ± 0.064

16.5 ± 19.5*

4

2

0

arguta-juice (x3)

0.94

0

  1. Significantly different from Group 1 at * p < 0.05