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Table 4 Comparison of the sensitivity of NM2009, NM3009, and TA1535/pSK1002 strains to nitroarenes and arylamines [7, 36]

From: Development and progress for three decades in umu test systems

Chemicals S9 TA1535/pSK1002 NM2009 NM3009
   Minimal concentration (ng/ml)a
1-nitropyrene 13 ND 0.2
3-nitrofluoranthene 10 ND 0.08
1,3-dinitropyrene 0.4 ND 0.1
1,6-dinitropyrene 1.4 ND 0.04
3,7-dinitrofluoranthene 1.2 ND 0.05
3,9-dinitrofluoranthene 1.8 ND 0.06
2-aminoanthracene + 8,400 400 ND
6-aminochrysene + 200 260 ND
Glu-P-1 + 100 80 ND
Trp-P-1 + 80 6 ND
MeAαC + 800 180 ND
MeIQ + 1 0.009 ND
  1. aThe concentration of chemicals that induced umuC gene expression by twofold over background levels
  2. ND, not determined