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Table 4 Comparison of the sensitivity of NM2009, NM3009, and TA1535/pSK1002 strains to nitroarenes and arylamines [7, 36]

From: Development and progress for three decades in umu test systems

Chemicals

S9

TA1535/pSK1002

NM2009

NM3009

  

Minimal concentration (ng/ml)a

1-nitropyrene

−

13

ND

0.2

3-nitrofluoranthene

−

10

ND

0.08

1,3-dinitropyrene

−

0.4

ND

0.1

1,6-dinitropyrene

−

1.4

ND

0.04

3,7-dinitrofluoranthene

−

1.2

ND

0.05

3,9-dinitrofluoranthene

−

1.8

ND

0.06

2-aminoanthracene

+

8,400

400

ND

6-aminochrysene

+

200

260

ND

Glu-P-1

+

100

80

ND

Trp-P-1

+

80

6

ND

MeAαC

+

800

180

ND

MeIQ

+

1

0.009

ND

  1. aThe concentration of chemicals that induced umuC gene expression by twofold over background levels
  2. ND, not determined