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Table 5 Comparison of genotoxicity activities of various chemicals in S. typhimurium TA1535/pSK1002 and NM5004 strains a [9, 60]

From: Development and progress for three decades in umu test systems

Chemicals NM5004 [GST(+)] TA1535/pSK1002 [GST(−)]
1,2-dibromoethane +++
N-(2,3-epoxypropyl)phthalimide +++ +
1,3-dichloroacetone ++ +
CH2I2 ++
1,2-epoxy-3-phenoxypropane +
2,3-epoxypropyl p-methxyphenyl ether +
1-bromo-2-chloroethane +
1-bromo-2,3-dichloropropane +
CH2BrCl +
CH2Br2 +
1,2-epoxy-3-(4′-nitrophenoxy)-propane ++
2,3-dibromo-1-chloropropane ± +
1,4-dibromo-2,3-epoxybutane + ++
1,2-epoxy-3-bromopropane +
1,2-epoxy-3-chloropropane ±
1,2,3,4-diepoxybutane + +
2,3-dibromopropionaldehyde + +
1,4-dibromo-2,3-dihydroxybutane ±
1,4-dibromobutane
1,3-dibromoacetone + +
2,3-dibromo-1-propanol ± ±
1,2-epoxy-4-bromobutane ± ±
CH2Cl2 ++
1,3-dibromo-2-propanol
1-bromo-2,3-propanediol
4-vinylcyclohexene dioxide
eyclohexene oxide
1,2-epoxybutane
1-bromo-2-fluoroethane
  1. a Potencies of chemicals in umu systems were ranked as follows: (−) 0–50; (±) 50–100; (+) 100–250; (++) 250–450; (+++) 450 for umu gene expression (units)