Table 5 Comparison of genotoxicity activities of various chemicals in S. typhimurium TA1535/pSK1002 and NM5004 strains a [9, 60]
From: Development and progress for three decades in umu test systems
Chemicals | NM5004 [GST(+)] | TA1535/pSK1002 [GST(−)] |
|---|---|---|
1,2-dibromoethane | +++ | − |
N-(2,3-epoxypropyl)phthalimide | +++ | + |
1,3-dichloroacetone | ++ | + |
CH2I2 | ++ | − |
1,2-epoxy-3-phenoxypropane | + | − |
2,3-epoxypropyl p-methxyphenyl ether | + | − |
1-bromo-2-chloroethane | + | − |
1-bromo-2,3-dichloropropane | + | − |
CH2BrCl | + | − |
CH2Br2 | + | − |
1,2-epoxy-3-(4′-nitrophenoxy)-propane | − | ++ |
2,3-dibromo-1-chloropropane | ± | + |
1,4-dibromo-2,3-epoxybutane | + | ++ |
1,2-epoxy-3-bromopropane | − | + |
1,2-epoxy-3-chloropropane | − | ± |
1,2,3,4-diepoxybutane | + | + |
2,3-dibromopropionaldehyde | + | + |
1,4-dibromo-2,3-dihydroxybutane | ± | − |
1,4-dibromobutane | − | − |
1,3-dibromoacetone | + | + |
2,3-dibromo-1-propanol | ± | ± |
1,2-epoxy-4-bromobutane | ± | ± |
CH2Cl2 | ++ | − |
1,3-dibromo-2-propanol | − | − |
1-bromo-2,3-propanediol | − | − |
4-vinylcyclohexene dioxide | − | − |
eyclohexene oxide | − | − |
1,2-epoxybutane | − | − |
1-bromo-2-fluoroethane | − | − |