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Fig. 9 | Genes and Environment

Fig. 9

From: Nitrative and oxidative DNA damage in infection-related carcinogenesis in relation to cancer stem cells

Fig. 9

Formation of 8-nitroguanine and expression of Oct3/4 in bladder tissues. The formation of 8-nitroguanine (red) and the expression of Oct3/4 (green) were assessed by double immunofluorescence staining [21]. In the merged image, co-localization of 8-nitroguanine and Oct3/4 is indicated in yellow. Biopsy and surgical specimens were obtained from normal subjects and patients with SH-induced cystitis and bladder cancer. Normal tissues and urinary bladder cancer tissues without SH-infection were obtained from a commercial urinary bladder tissue array (Biomax.us, USA)

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Genes and Environment

ISSN: 1880-7062

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