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Table 3 Frequency of CYP1A1 variants in relation to smoking habit in patients and control

From: Genetic polymorphisms of human cytochrome P450 CYP1A1 in an Egyptian population and tobacco-induced lung cancer

CYP1A1 Variant

Control

Patients

Chi-square

P-value

Non-smoker

Smoker

Non-smoker

Smoker

  

N = 120

N = 30

N = 56

N = 93

  

CYP1A1*2C

N (%)

18 (15)

1 (3.3)

7 (12.5)

10 (10.8)

18.9

0.03a

CYP1A1*4

N (%)

29(24.2)

4 (13.3)

15 (26.8)

31 (33.3)

CYP1A1*2C/*4

N (%)

0 (0)

0 (0)

3 (5.4)

1 (1.1)

CYP1A1*1 (wild type)

N (%)

73 (60.8)

25 (83.3)a

31 (55.4)

51 (54.8)

  1. aSignificant P