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Table 4 Association of CYP1A1 polymorphisms and smoking with lung cancer risk

From: Genetic polymorphisms of human cytochrome P450 CYP1A1 in an Egyptian population and tobacco-induced lung cancer

CYP1A1 Variant

Non-smokers

Smokers

OR

95% CI

P-value

N = 56

N = 93

N (%)

N (%)

CYP1A1*2C

7 (12.5)

10 (10.8)

1.19

(0.42–3.32)

0.75

CYP1A1*4

15 (26.8)

31 (33.3)

0.73

(0.35–1.52)

0.20

CYP1A1*2C/*4

3 (5.4)

1 (1.1)

5.21

(0.53–51.3)

0.12

CYP1A1*1 (wild type)

31 (55.4)

51 (54.8)

0.98

(0.50–1.91)

0.95

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Genes and Environment

ISSN: 1880-7062

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