Fig. 4

CA and SCE incidences in WT TK+/- and KO TK+/- cells treated with MMC. a CA assay and (b) SCE assay. White and black boxes represent WT TK+/- and KO TK+/- cells, respectively. Both results were drawn from single experiments. Error bars indicate the standard deviation from SCEs of 50 metaphase cells, and * denotes the statistical significance between WT TK+/- and KO TK+/- cells at the same dose concentrations (P < 0.05)