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Fig. 1 | Genes and Environment

Fig. 1

From: New insight for metformin against bladder cancer

Fig. 1

Proposed mechanisms of anti-carcinogenic effects of metformin against bladder cancer: (1) metformin induces growth inhibition, (2) metformin regulates insulin and glucose levels, (3) metformin induce cell death, (4) metformin potentiates the cytotoxicity of chemotherapeutic drugs, (5) metformin’s association with oxidative stress, DNA Damage Response (DDR), (6) immune and hypothalamic effects of metformin and (7) autophagy effects of metformin

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