Fig. 1
From: Modulation of benzo[a]pyrene–DNA adduct formation by CYP1 inducer and inhibitor
Alteration of BaP–DNA adduct formation by CYP subtypes and AhR activators. Effect of AhR activator on BaP–DNA adduct formation in HepG2 cells. HepG2 cells were concomitantly treated with BaP (5 or 10 μM), indirubin (IND, 100 nM), quinizarin (QNZ, 10 μM), omeprazole (OME, 100 μM), or TCDD (10 nM) for 16 h. After incubation, DNA was purified and BaP–DNA adducts were analyzed. This figure is adapted from data reported previously [24]