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Table 1 Comparison of NHEJ factors in S. cerevisiae and mammalian cells

From: Unique molecular mechanisms for maintenance and alteration of genetic information in the budding yeast Saccharomyces cerevisiae

S. cerevisiae

Mammalian

Yku70 (Hdf1)/Yku80 (Hdf2)

Ku70/Ku80

–

DNA-PKcs

Dnl4/Lif1

Lig IV/XRCC4

Nej1

XLF

Pol4

DNA polymerase μ or λ

Pso2?

Artemis

Rad27

FEN-1

Mre11/Rad50/Xrs2

Mre11/Rad50/Nbs1