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Table 1 Comparison of NHEJ factors in S. cerevisiae and mammalian cells

From: Unique molecular mechanisms for maintenance and alteration of genetic information in the budding yeast Saccharomyces cerevisiae

S. cerevisiae Mammalian
Yku70 (Hdf1)/Yku80 (Hdf2) Ku70/Ku80
– DNA-PKcs
Dnl4/Lif1 Lig IV/XRCC4
Nej1 XLF
Pol4 DNA polymerase μ or λ
Pso2? Artemis
Rad27 FEN-1
Mre11/Rad50/Xrs2 Mre11/Rad50/Nbs1
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Genes and Environment

ISSN: 1880-7062

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