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Table 1 Mutagenicity of X-ray irradiation in urate-null mutants and wild-type flies

From: Increase of somatic cell mutations in oxidative damage-sensitive drosophila

Dose (Gy)

Survival (%)

No. of wings

No. of spots (spots/wing)

Small

Large

Total

Exp. 1

 y v ma-l; mwh × Oregon-R F1 females (uric acid +)

  0

100

95

22 (0.23)

9 (0.09)

31 (0.33)

  3

98

94

47 (0.50)

99 (1.05)**

146 (1.55)*

 y v ma-l; mwh × y v ma-l F1 females (uric acid -)

  0

100

100

36 (0.36)

20 (0.20)

56 (0.56)

  3

102

100

147 (1.47)**

173 (1.73)**

320 (3.20)**

Exp. 2

 y v ma-l; mwh × Oregon-R F1 females (uric acid +)

  0

100

100

15 (0.15)

5 (0.05)

20 (0.15)

  10

112

102

277 (2.72)**

454 (4.45)**

731 (7.17)**

 y v ma-l; mwh × y v ma-l F1 females (uric acid -)

  0

100

102

41 (0.40)

11 (0.11)

52 (0.51)

  10

93

100

777 (7.77)**

1134 (11.3)**

1911 (19.1)**

  1. *P ≤ 0.05, **P ≤ 0.01, a significant increase in comparison to the corresponding control