Table 3 Mutagenicity of MMC in urate-null mutants and wild-type flies
From: Increase of somatic cell mutations in oxidative damage-sensitive drosophila
Dose (mM) | Survival (%) | No. of wings | No. of spots (spots/wing) | ||
|---|---|---|---|---|---|
Small | Large | Total | |||
y v ma-l; mwh × Oregon-R F1 females (uric acid +) | |||||
 0 | 100 | 161 | 17 (0.11) | 3 (0.02) | 20 (0.12) |
 0.05 | 87 | 151 | 866 (5,74)** | 349 (2.31)** | 1215 (8.05)** |
 0.1 | 105 | 181 | 1816 (10.0)** | 611 (3.38)** | 2427 (13.4)** |
y v ma-l; mwh × y v ma-l F1 females (uric acid -) | |||||
 0 | 100 | 113 | 65 (0.58) | 10 (0.09) | 75 (0.66) |
 0.05 | 44 | 50 | 769 (15.4)** | 298 (5.96)* | 1067 (21.3)** |
 0.1 | 56 | 64 | 2038 (31.8)** | 488 (7.63)** | 2529 (39.5)** |