From: Increase of somatic cell mutations in oxidative damage-sensitive drosophila
Dose (mM) | Survival (%) | No. of wings | No. of spots (spots/wing) | ||
---|---|---|---|---|---|
Small | Large | Total | |||
Exp. 1 | |||||
 y v ma-l; mwh × Oregon-R F1 females (uric acid +) | |||||
  0 | 100 | 140 | 17 (0.12) | 2 (0.01) | 19 (0.14) |
  1 | 92 | 164 | 29 (0.18) | 6 (0.04) | 35 (0.21) |
  3 | 90 | 158 | 38 (0.24)* | 11 (0.07) | 49 (0.31)** |
  5 | 66 | 114 | 41 (0.36)** | 6 (0.05) | 47 (0.41)** |
 y v ma-l; mwh × y v ma-l F1 females (uric acid -) | |||||
  0 | 100 | 135 | 49 (0.36) | 6 (0.04) | 55 (0.41) |
  1 | 120 | 169 | 111 (0.66)** | 21 (0.12)* | 132 (0.78)** |
  3 | 76 | 108 | 74 (0.69)** | 25 (0.23)** | 99 (0.92)** |
  5 | 30 | 44 | 57 (1.30)** | 16 (0.36)** | 73 (1.66)** |
Exp. 2 | |||||
 y v ma-l; mwh × Oregon-R F1 females (uric acid +) | |||||
  0 | 100 | 151 | 19 (0.13) | 4 (0.03) | 23 (0.15) |
  1 | 85 | 132 | 43 (0.33)** | 19 (0.14)** | 62 (0.47)** |
  3 | 72 | 103 | 43 (0.42)** | 14 (0.14)** | 57 (0.55)** |
  5 | 52 | 79 | 18 (0.23) | 4 (0.05) | 22 (0.28) |
 y v ma-l; mwh × y v ma-l F1 females (uric acid -) | |||||
  0 | 100 | 117 | 46 (0.39) | 11 (0.09) | 57 (0.49) |
  1 | 113 | 136 | 123 (0.90)** | 36 (0.26)** | 159 (1.17)** |
  3 | 105 | 125 | 209 (1.67)** | 63 (0.50)** | 272 (2.18)** |
  5 | 43 | 46 | 100 (2.17)** | 29 (0.63)** | 129 (2.80)** |
Exp. 3 | |||||
 mwh, ry506 × ry+ F1 females (uric acid +) | |||||
  0 |  | 92 | 128 (1.39) | 11 (0.12) | 139 (1.51) |
  1 |  | 62 | 118 (1.90)** | 30 (0.48)** | 148 (2.39)** |
 mwh, ry506 × ry506 F1 females (uric acid -) | |||||
  0 |  | 112 | 114 (1.31) | 30 (0.34) | 144 (1.66) |
  1 |  | 50 | 131 (3.12)** | 57 (1.36)** | 188 (4.48)** |
Exp. 4 | |||||
 mwh, ry506 × ry+ F1 females (uric acid +) | |||||
  0 | 100 | 82 | 110 (1.34) | 13 (0.16) | 123 (1.50) |
  1 | 87 | 88 | 135 (1.53) | 28 (0.32) | 163 (1.85)* |
 mwh, ry506 × ry506 F1 females (uric acid -) | |||||
  0 | 100 | 90 | 123 (1.37) | 15 (0.17) | 138 (1.53) |
  1 | 96 | 86 | 184 (2.14)** | 51 (0.59)** | 235 (2.73)** |