From: Increase of somatic cell mutations in oxidative damage-sensitive drosophila
NDMA (mM) | Addition of uric acid | Uric acid content in flies(nmol/mg protein) | No. of flies | No. of wings | No. of spots (spots/wing) | ||
---|---|---|---|---|---|---|---|
Small | Large | Total | |||||
y v ma-l; mwh × Oregon-R F1 females (uric acid +) | |||||||
 0 | – | 256.6 | 79 | 100 | 9 (0.09) | 2 (0.02) | 11 (0.11) |
+ | 321.2 | 69 | 100 | 7 (0.07) | 2 (0.02) | 9 (0.09) | |
 0.5 | – | 266.0 | 81 | 100 | 79 (0.79) | 31 (0.31) | 110 (1.10) |
+ | 371.1 | 72 | 100 | 38 (0.38)§§ | 13 (0.13)§ | 51 (0.51) §§ | |
y v ma-l; mwh × y v ma-l F1 females (uric acid -) | |||||||
 0 | – | 0.08 | 68 | 100 | 23 (0.23) | 6 (0.06) | 56 (0.56) |
+ | 11.3 | 38 | 66 | 12 (0.18) | 4 (0.06) | 16 (0.24) | |
 0.5 | – | 0.31 | 64 | 100 | 174 (1.74) | 55 (0.55) | 229 (2.29) |
+ | 11.1 | 32 | 54 | 88 (1.63) | 24 (0.44) | 112 (2.07) |