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Fig. 10 | Genes and Environment

Fig. 10

From: Negative and positive control ranges in the bacterial reverse mutation test: JEMS/BMS collaborative study

Fig. 10

Positive control counts, and their subsequent analysis, for Escherichia coli strain WP2uvrA with and without S9 mix. Histograms show the negative control counts, and the curves indicate the expected values calculated based on the assumption that the negative control counts follow a normal distribution, without (a) and with (b) S9 mix. Scatter plots showing the negative control counts generated by each participating laboratory without (c) and with (d) S9 mix are also shown, where the inner horizontal lines (−˙-) indicate the mean ± 2× standard deviation (SD), and outer horizontal lines (−--) indicate the mean ± 3× SD. The data shown in panels (a) to (d) are taken from the study conducted in 2016. The doses used were 0.01 μg/plate for SA in the absence of S9 mix, and 10 μg/plate for 2AA in the presence of S9 mix

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Genes and Environment

ISSN: 1880-7062

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