Negative and positive control ranges in the bacterial reverse mutation test: JEMS/BMS collaborative study

Genes and Environment

Table 1 Statistics for negative control data obtained in this study

Statistics	TA100		TA98		TA1535		TA1537		WP2uvrA
Statistics	-S9	+S9	-S9	+S9	-S9	+S9	-S9	+S9	-S9	+S9
No. of data	26	26	26	26	25	25	25	25	23	23
Mean	102	115	21	28	10	10	9	13	24	28
SD	17.34	20.06	8.23	6.66	3.10	3.17	2.95	4.60	4.87	7.33
Variance	312.57	418.66	70.36	46.06	10.01	10.48	9.08	22.01	24.75	56.23
Min	69	78	12	17	6	5	3	6	14	17
Max	132	156	40	42	19	18	15	23	33	47
Kurtosis	− 0.63	− 0.64	0.58	−0.73	0.88	0.64	− 0.63	− 0.24	0.04	0.29
Skewness	−0.09	0.30	1.22	0.40	0.98	0.80	0.15	0.54	−0.25	0.82
2SD-	68	74	5	15	4	4	3	4	14	13
2SD+	137	156	37	42	17	17	15	23	33	43
3SD-	50	54	−4	8	1	1	0	0	9	6
3SD+	154	175	46	48	20	20	17	27	38	50

Min minimum count, max maximum count, 2SD− mean − 2× standard deviation, 2SD+ mean + 2× standard deviation, 3SD− mean − 3× standard deviation, 3SD+ mean + 3× standard deviation

ISSN: 1880-7062