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Table 2 Statistics for positive control data obtained in this study

From: Negative and positive control ranges in the bacterial reverse mutation test: JEMS/BMS collaborative study

Statistics TA100 TA98 TA1535 TA1537 WP2uvrA
-S9 +S9 -S9 +S9 -S9 +S9 -S9 +S9 -S9 +S9
Positive control article and dose (μg/plate) AF-2 (0.01) 2AA (1.0) AF-2 (0.1) 2AA (0.5) SA (0.5) 2AA (2.0) 9AA (80) 2AA (2.0) AF-2 (0.01) 2AA (10)
No. of data 27 27 27 27 26 26 26 26 24 24
Mean 541 1028 481 386 376 265 331 167 133 650
SD 157.23 331.4 119.21 128.07 108.98 93.99 150.7 65.38 41.60 282.98
Min 336 521 217 166 135 93 121 61 74 200
Max 937 1656 684 611 593 488 671 368 243 1285
Kurtosis 0.13 −1.28 −0.30 −1.09 −0.03 −0.01 0.00 2.17 0.80 −0.23
Skewness 0.80 0.25 −0.45 0.05 −0.21 0.15 0.67 0.89 1.05 0.55
2SD- 226 365 243 130 158 77 29 36 50 84
2SD+ 855 1691 719 643 594 453 632 298 216 1216
3SD- 69 34 123 2 49 −17 − 122 −29 8 −199
3SD+ 1013 2022 839 771 703 547 783 363 258 1499
  1. Min minimum count, max maximum count, 2SD− mean − 2× standard deviation, 2SD+ mean + 2× standard deviation, 3SD− mean − 3× standard deviation, 3SD+ mean + 3× standard deviation, AF-2 2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide, 2AA 2-aminoanthracene, SA sodium azide, 9AA 9-aminoacridine hydrochloride