Table 3 Spectra of mutations detected in the supF gene (experiment 1)a
From: Analysis of large deletion mutations induced by abasic site analog in human cells
| Â | G | GO | THF | Â |
|---|---|---|---|---|
point mutations at position 122 | ||||
 G:C - > A:Tb | 0 (0) | 0 (0) | 0 (0) |  |
 G:C - > T:Ac | 3 (10) | 23 (46) | 9 (15) |  |
 G:C - > C:Gd | 0 (0) | 8 (16) | 11 (18) |  |
 deletion | 0 (0) | 1 (2) | 11 (18) |  |
mutations at other positions | ||||
 transition | ||||
  A:T - > G:C | 1 (3) | 0 (0) | 0 (0) |  |
  G:C - > A:T | 16 (53) | 8 (16) | 17 (28) |  |
 transversion | ||||
  A:T - > T:A | 0 (0) | 0 (0) | 0 (0) |  |
  A:T - > C:G | 3 (10) | 2 (4) | 0 (0) |  |
  G:C - > T:A | 9 (30) | 6 (12) | 11 (18) |  |
  G:C - > C:G | 4 (13) | 4 (8) | 19 (32) |  |
 small insertion (1–2 bp) | 1 (3) | 1 (2) | 0 (0) |  |
 large insertion (> 2 bp) | 6 (20) | 1 (2) | 1 (2) |  |
 small deletion (1–2 bp) | 0 (0) | 0 (0) | 1 (2) |  |
 large deletion (> 2 bp) | 12 (40) | 8 (16) | 12 (20) |  |
 others | 0 (0) | 0 (0) | 2 (3)e |  |
total mutations | 55 | 62 | 94 | Â |
total colonies analyzed | 30 (100) | 50 (100) | 60 (100) | Â |