Change over time of the mutagenicity in the lungs of gpt delta transgenic mice by extract of airborne particles collected from ambient air in the Tokyo metropolitan area

Table 3 Mutagenicity and concentration of TSP in Tokyo metropolitan area in 1980, 1990 and 2010

Sampling time	In vivo mutagenic potency^a	Concentration of TSP^b	In vitro mutagenic potency^c
1980	0.8 × 10⁻⁵	0.095	1302
1990	1.9 × 10⁻⁵	0.080	870
2010	0.93 × 10⁻⁵	0.036

^agpt average mutation frequency per mg extract
^bmg/m³
^cHis⁺ revertants per mg extract in TA98 without S9 (representative of Ames tests). Data from the reference [38]

ISSN: 1880-7062