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Fig. 7 | Genes and Environment

Fig. 7

From: High-content imaging analyses of γH2AX-foci and micronuclei in TK6 cells elucidated genotoxicity of chemicals and their clastogenic/aneugenic mode of action

Fig. 7

Results for the clastogens that need metabolic activation: benzo[a]pyrene (BaP), cyclophosphamide (CP), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine hydrochloride (PhIP). MNed cells were measured after treatment with each chemical and with S9 mix for 3 h followed by recovery culture for 21 h. γH2AX foci were measured after 4 h treatment with each chemical with S9 mix. Both MNed cells and γH2AX foci were increased by all of the clastogens

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Genes and Environment

ISSN: 1880-7062

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