Chloroethylating anticancer drug-induced mutagenesis and its repair in Escherichia coli

Genes and Environment

Table 1 E. coli KA796 mutants used in this study and their spontaneous mutant frequencies

Strain^a	Relevant genotype	Spontaneous mutant frequency^b (× 10^− 7)	Ref.
NR12999	KA796, uvrA277::Tn10	0.24 ± 0.16	[18]
KT01121	KA796, ada-10::Tn10, ogt::cat	0.78 ± 0.27	[19]
NR12896	KA796, mutS201::Tn5	59.6 ± 11.4	[18]
NR11102	KA796, mutL211::Tn5	22.5 ± 9.63	[18]
NR12897	KA796, mutH471::Tn5	43.0 ± 16.5	[18]
NR11312	KA796, recA56, srl::Tn10	0.16 ± 0.1	[18]
ZA2102	uvrA6, malE::Tn5	< 0.1	[20]
SW102	uvrA6, malE::Tn5, recA56, srl::Tn10	0.1 ± 0.5	This study

a: All mutants contain CC102 F’episome
b: All spontaneous mutant frequencies shown in this table were measured in this study

ISSN: 1880-7062