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Fig. 5 | Genes and Environment

Fig. 5

From: Development of novel and safer anti-breast cancer agents, SS1020 and SS5020, based on a fundamental carcinogenic research

Fig. 5

Uterotrophic effects of antiestrogens (left panel, SS1020 and its related compounds; right panel, SS5020 and its related compounds) in ovariectomized SD rats. Ovariectomized rats were subcutaneously treated with each test compound (0.3 μmol/rat/d of 17β-estradiol, or equivalent molar of test compound), and uterine wet weight was measured. TAM, 4-OH TAM, TOR, and OSP clearly increased uterine wet weight. RAL, GW, SP, and SS1010 exerted moderate uterotrophic effects. No detectable effects were observed in SS1020 [9] and SS5020 [10]

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Genes and Environment

ISSN: 1880-7062

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