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Fig. 6 | Genes and Environment

Fig. 6

From: Development of novel and safer anti-breast cancer agents, SS1020 and SS5020, based on a fundamental carcinogenic research

Fig. 6

32P-postlabeling/PAGE analysis of SS1020, SS5020 and related anti-estrogens. Female SD rats were orally treated with test compound (20 mg/kg/d of TAM, or equivalent molar of test compound), and liver DNA was used for DNA adduct analysis. TAM treatment clearly formed dG-TAM adducts, whereas SS1020, SS5020 or TOR treatment didn’t observed any detectable DNA adducts [9, 10]

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Genes and Environment

ISSN: 1880-7062

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