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Fig. 1 | Genes and Environment

Fig. 1

From: Effect of MMP-2 gene silencing on radiation-induced DNA damage in human normal dermal fibroblasts and breast cancer cells

Fig. 1

Effect of MMP-2 gene silencing in pMMP-2 transfected irradiated HDF cells. a Graphical representation of viability of HDF cells on irradiation (2-10Gy) analyzed by MTT assay. b Graphical representation of viability in pMMP-2 transfected HDF cells at single large dose i.e. 10Gy analyzed by MTT assay. c Morphological characterization under phase contrast microscopy of HDF cells. d Fluorescence micrographs of dead green stain in HDF cells in control, irradiated and pMMP-2sh transfected irradiated HDF cells. e Representative images γH2AX foci obtained by immunofluorescence microscopy in HDF cells in control, irradiated HDF cells and pMMP-2 transfected irradiated HDF cells. f Representative images of alkaline comet assay performed in HDF cells in control, irradiated and pMMP-2 transfected irradiated HDF cells

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