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Fig. 2 | Genes and Environment

Fig. 2

From: Effect of MMP-2 gene silencing on radiation-induced DNA damage in human normal dermal fibroblasts and breast cancer cells

Fig. 2

Effect of MMP-2 gene silencing in pMMP-2 transfected irradiated MCF-7 cells. a Graphical representation of viability of MCF-7 cells radiation (2-10Gy) analyzed by MTT assay. b Graphical representation of viability of pMMP-2 transfected MCF-7 cells at single large dose i.e. 10Gy analyzed by MTT assay. c Morphological characterization under phase contrast microscopy of MCF-7 cells. d Fluorescence micrographs of dead green stain in MCF-7 cells in control, irradiated and pMMP-2 transfected irradiated MCF-7 cells. e Representative images γH2AX foci obtained by immunofluorescence microscopy in MCF-7 cells in control, irradiated MCF-7 cells and pMMP-2 transfected irradiated MCF-7 cells. f Representative images of alkaline comet assay performed in MCF-7 cells in control, irradiated and pMMP-2 transfected irradiated MCF-7 cells

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