Fig. 4From: Acid-specific formaldehyde donor is a potential, dual targeting cancer chemotherapeutic/chemo preventive drug for FANC/BRCA-mutant cancerSensitivity of human cultured cells proficient and deficient in HR to formaldehyde or HMTA. Survival curves of MCF12 (BRCA1-proficient) breast epithelial cells and and sum149 (BRCA1-deficient) breast cancer cells exposed to formaldehyde (a) or HMTA (b) under neutral conditions. (c) Survival curves of isogenic FancC-proficient or deficient RKO human colon cancer cells exposed to HMTA under neutral conditionsBack to article page