Skip to main content
Fig. 1 | Genes and Environment

Fig. 1

From: Effect of episomally encoded DNA polymerases on chemically induced mutagenesis at the hisG46 target in Ames test

Fig. 1

Comparison of spontaneous revertant counts in the newly developed Ames tester strains. The bar graph demonstrates levels of spontaneous mutagenesis in the classical Ames tester strains (TA1535, TA100) and their PolV-deficient derivatives (YG5151, YG9056) compared to the newly constructed strains overexpressing the activated forms of PolRI* (MucA’ + MucB, YG9028), the SamA’B polymerase (SamA’ + SamB, YG9029) and their chimerical combinations (MucA’ + SamB, YG9032; SamA’ + MucB, YG9033). The darker bars on the right side of the data point pairs represent the numbers of revertants at higher DNA polymerase expression levels induced by IPTG

Back to article page