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Fig. 3 | Genes and Environment

Fig. 3

From: Effect of episomally encoded DNA polymerases on chemically induced mutagenesis at the hisG46 target in Ames test

Fig. 3

Dose dependence of mutagenesis induced by MMS. Methyl methanesulfonate (MMS) has been applied at the doses indicated on the X-axis to the classical Ames tester strains and their PolV-deficient derivatives (left panel) or to the new Ames tester strains overexpressing the activated PolRI* and SamA’B polymerase subunits from the uninduced (middle panel) or induced (right panel) lac promoter. The induced His+ revertant counts displayed on the Y-axis were calculated by subtracting the average spontaneous revertant number for a given strain from the total number of revertants per plate values. The strains used are shown in the graph legend and described in Table 1 in detail

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