Isolation and structure elucidation of constituents of Citrus limon, Isodon japonicus, and Lansium domesticum as the cancer prevention agents

Table 2 Antimutagenic activity of furanocoumarins (11, 12, 14, and 15) against Trp-P-1 (0.04 μg/plate) using the Ames test [4]^a

	Inhibition % (Based on number of revertant colonies)
	3.1 nmol/plate	6.3 nmol/plate	12.5 nmol/plate	25 nmol/plate	50 nmol/plate
Furanocoumarins
11	22%	13.9%	25.0%	31.5%	40.9%
12	27.0%	35.9%	51.6%	59.5%	74.7%
14	25.0%	40.5%	49.7%	62.8%	73.7%
15	5.6%	5.6%	18.1%	36.6%	51.2%

^a No compound showed antibacterial activity [< 5.0% inhibition at highest concentration] against the S. typhimurium TA98 strain at the tested concentrations

ISSN: 1880-7062