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Table 4 Antimutagenic activity of furanocoumarins (11, 12, 14, and 15) against PhIP (1.0 μg/plate) using the Ames test [4]a

From: Isolation and structure elucidation of constituents of Citrus limon, Isodon japonicus, and Lansium domesticum as the cancer prevention agents

 

Inhibition % (Based on number of revertant colonies)

3.1 nmol/plate

6.3 nmol/plate

12.5 nmol/plate

25 nmol/plate

50 nmol/plate

Furanocoumarins

11

22.0%

28.0%

29.7%

46.3%

64.0%

12

47.0%

57.7%

68.5%

73.4%

83.4%

14

34.0%

41.7%

51.7%

67.6%

70.1%

15

47.1%

62.1%

65.3%

69.6%

78.7%

  1. a No compound showed antibacterial activity [< 5.0% inhibition at highest concentration] against the S. typhimurium TA98 strain at the tested concentrations