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Table 4 Antimutagenic activity of furanocoumarins (11, 12, 14, and 15) against PhIP (1.0 μg/plate) using the Ames test [4]a

From: Isolation and structure elucidation of constituents of Citrus limon, Isodon japonicus, and Lansium domesticum as the cancer prevention agents

  Inhibition % (Based on number of revertant colonies)
3.1 nmol/plate 6.3 nmol/plate 12.5 nmol/plate 25 nmol/plate 50 nmol/plate
Furanocoumarins
11 22.0% 28.0% 29.7% 46.3% 64.0%
12 47.0% 57.7% 68.5% 73.4% 83.4%
14 34.0% 41.7% 51.7% 67.6% 70.1%
15 47.1% 62.1% 65.3% 69.6% 78.7%
  1. a No compound showed antibacterial activity [< 5.0% inhibition at highest concentration] against the S. typhimurium TA98 strain at the tested concentrations