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Fig. 1 | Genes and Environment

Fig. 1

From: Construction of reporter gene assays using CWP and PDR mutant yeasts for enhanced detection of various sex steroids

Fig. 1

Responses of reporter gene assay yeast strains expressing human ERα, ERβ, PR, and AR to endogenous sex steroid hormones. ERα and ERβ assay yeasts (W303a and cwp1Δcwp2Δ) were exposed to E1 (A), E2 (B), and E3 (C). PR (W303a, cwp1Δpdr5Δ, and cwp1Δcwp2Δ) and AR (W303a, cwp1Δpdr5Δ, and pdr5Δpdr10Δ) assay yeasts were exposed to PS (D), TS (E), and DHT (F), respectively. The ligand-dependent induction of β-gal was measured as described in the Methods section. Data represent the mean ± SD of triplicate experiments

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Genes and Environment

ISSN: 1880-7062

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