Fig. 8

Detection of synthetic sex hormone activities from oral tablets. Organic compounds were extracted from oral pharmaceutical tablets Lunabell® and concentrated. Using serially diluted samples as ligands, yeast reporter gene assays were performed using yeasts expressing ERα and ERβ (W303a and cwp1Δcwp2Δ), PR (W303a, cwp1Δpdr5Δ, and cwp1Δcwp2Δ), and AR (W303a, cwp1Δpdr5Δ, and pdr5Δpdr10Δ): ERα (A), ERβ (B), PR (C), and AR (D). Data represent the mean ± SD of triplicate experiments