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Fig. 4 | Genes and Environment

Fig. 4

From: DNA hypomethylation drives changes in MAGE-A gene expression resulting in alteration of proliferative status of cells

Fig. 4

Cells expressing MAGE-A genes have a proliferative advantage. a mRNA expression MAGE-A genes in HEK (black), HEK OE (HEK cells that have been transduced with lentivirus encoding the indicated MAGE gene, lined), HCT116 (grey) as determined by RT-qPCR. Data shown are mean ± S.D. from n = 3 experiments. b Western blot showing expression of myc-tagged MAGE-A proteins in the lysates of HEK OE cell lines. Tubulin is used as loading control. c Population doubling of HEK cells or HEK cells expressing specific and indicated MAGEs over a period of 9 days. Cells were counted every 24 hours to determine the population doubling. Data shown are mean ± SEM from n = 3 experiments. P values were determined from Students' t-test and * p < 0.01 and # is not-significant (NS)

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Genes and Environment

ISSN: 1880-7062

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