Fig. 6

Specific MAGE-A genes confer chemo-resistance. a HEK cells expressing vector control or MAGE-A genes were treated with 100 μM 5-fluorouracil and cell viability measured at 72 hours post-treatment using the end point Cell-Titer Glo assay. The luminescence of cells treated with DMSO was set to 100% viability. Data shown are mean ± S.D. from n = 3 experiments. P values were determined from Students' t-test and * p < 0.01, ** p <0.001 and # is not significant. b HEK cells expressing vector control or MAGE-A genes were treated with 100 μM sodium arsenite and cell viability measured at 72 hours post-treatment using the end point Cell-Titer Glo assay. The luminescence of cells treated with DMSO was set to 100% viability. Data shown are mean ± S.D. from n = 3 experiments. P values were determined from Students' t-test and * p < 0.01