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Fig. 1 | Genes and Environment

Fig. 1

From: Oxidation resistance 1 functions in the maintenance of cellular survival and genome stability in response to oxidative stress-independent DNA damage

Fig. 1

Sensitivity to MMS and heavy-ion beams. a-c Quantification of cellular survival. OXR1-depleted cells (shOXR1; closed square) and control cells (shLuci; open square) were (a) exposed constitutively to MMS (80, 160 or 320 μM) for 11 days, or irradiated with (b) carbon-ion beams (0, 2, 4 or 6 Gy, 290 MeV/nucleon, 87.0 keV/μm) or (c) iron-ion beams (0, 1, 3 or 5 Gy, 500 MeV/nucleon, 200 keV/μm). Cellular survival was analyzed by the colony formation assay. Means ± s.d. of n = three independent experiments, * p < 0.05, two-tailed Student’s t-test

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