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Table 1 Flavor chemicals in which Ames test was newly conducted.

From: Screening for Ames mutagenicity of food flavor chemicals by (quantitative) structure-activity relationship

No.

JECFA No.

Chemical Name

CAS No.

Purity (%)

Supplier

Categorya

I

470

2-[(methylthio)methyl]-2-butenal

40878-72-6

98.1

T. HASEGAWA CO.,LTD.

Aliphatic higher aldehydes

II

687

4'-methoxycinnamaldehyde

1963-36-6

98

Alfa Aesar

Aromatic aldehydes

III

1208

4-methyl-2-pentenal

5362-56-1

99.2

T. HASEGAWA CO., LTD.

Aliphatic higher aldehydes

IV

1451

4-methoxy-2,5-dimethyl-3(2H)-furanone

4077-47-8

97

Tokyo Chemical Industry Co.,Ltd.

Ketones

V

1456

2,5-dimethyl-4-oxo-3(5H)-furyl acetate

4166-20-5

>95

Takata Koryo Co., Ltd.

Esters

VI

1506

3-acetyl-2,5-dimethylfuran

10599-70-9

98

Tokyo Chemical Industry Co., Ltd.

Ketones

VII

2101

furfuryl formate

13493-97-5

>98.9

T. HASEGAWA CO., LTD.

Esters

VIII

2144

methyl beta-phenylglycidate

37161-74-3

99.8

T. HASEGAWA CO., LTD.

Esters

IX

2157

6-methoxyquinoline

5263-87-6

98.9

Tokyo Chemical Industry Co., Ltd.

Ethers

X

-

2-methylquinoline

91-63-4

98

Tokyo Chemical Industry Co., Ltd.

Not classified b

  1. a Eighteen categories (and other than specified else) classified according to their substructures defined in the Japanese Food Sanitation Law
  2. b Not applicable to flavor chemical in Japan