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Table 2 The gpt mutation frequency in the livers of mice administered TiO2-P25 90 days after the last administration

From: Genotoxicity assessment of titanium dioxide nanoparticle accumulation of 90 days in the liver of gpt delta transgenic mice

TiO2-P25Total populationNumber of mutationsMutation frequency (× 10−6)
 Mean ± SD
0 mg/kg1,005,00011.00 
1,215,00054.12 
996,00022.01 
1,242,00043.22 
1,074,00043.72 
1,530,00053.272.89 ± 1.17
2 mg/kg1,065,00076.57 
468,000817.09 
1,230,00043.25 
1,089,00010.92 
1,446,00042.77 
1,167,00065.145.96 ± 5.80
10 mg/kg846,00036.57 
912,00053.55 
711,00025.48 
771,00042.81 
1,506,00025.19 
1,380,00051.333.66 ± 1.54
50 mg/kg717,00068.37 
552,00059.06 
909,00033.30 
1,011,00054.95 
1,314,00043.045.74 ± 2.82