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Fig. 5 | Genes and Environment

Fig. 5

From: Radio-adaptive response and correlation of non-homologous end joining repair gene polymorphisms [XRRC5 (3R/2R/1R/0R), XRCC6(C/G) and XRCC7 (G/T)] in human peripheral blood mononuclear cells exposed to gamma radiation

Fig. 5

Line graph showing dose response, repair kinetics and mRNA expression of XRCC7 (PRKDC) among 20 donors and their correlation with each genotype. a Dose response curve for DNA damage at different doses for 20 donors. X-axis represents dose (Gy) whereas Y-axis represents DNA damage (Mean ± SEM) in terms of DNA in tail (%). Groups were created amongst 20 donors on the basis of genotypes. b Repair kinetics for 20 donors at various post-irradiation time intervals. X-axis represents post-irradiation time (min) whereas Y-axis represents DNA damage (Mean ± SEM) in terms of DNA in tail (%). Groups were created amongst 20 donors on the basis of genotypes. c mRNA expression of XRCC7 (PRKDC) at different doses for 20 donors. X-axis represents dose (Gy) and Y-axis represents relative XRCC7 (PRKDC) mRNA expression (Mean ± SEM) at 4 h post-irradiation. Groups were created amongst 20 donors on the basis of genotype. d mRNA expression (Mean ± SEM) of XRCC7 (PRKDC) for 20 donors at different post-irradiation time. X-axis represents time (min) and Y-axis represents relative expression. Groups were created amongst 20 donors on the basis of genotype

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Genes and Environment

ISSN: 1880-7062

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