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Fig. 7 | Genes and Environment

Fig. 7

From: Standard protocol for the PIGRET assay, a high-throughput reticulocyte Pig-a assay with an immunomagnetic separation, used in the interlaboratory trial organized by the Mammalian Mutagenicity Study Group of the Japanese Environmental Mutagen and Genome Society

Fig. 7

Example of PIGRET assay results. a PIGRET assays were conducted at 0 (pretreatment), 1, 2, and 4 weeks after a single oral administration of PBS (negative control; open circles), 10 mg/kg ENU (filled squares), or 40 mg/kg ENU (open squares). b %RET analysis results at 0, 1, 2, and 4 weeks. This study was conducted at Teijin Pharma Limited, and the result of PIGRET assay was reported as the reference site response for the MMS/JEMS collaborative study (Step 1) [2]. The %RET data have not been previously published

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Genes and Environment

ISSN: 1880-7062

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