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Table 1 Criteria for grading lung fibrosis

From: Dynamic assessing silica particle-induced pulmonary fibrosis and associated regulation of long non-coding RNA expression in Wistar rats

Grade of fibrosis Histological features
0 Normal lung
1 Minimal fibrous thickening of alveolar or bronchiolar walls with a few of inflammatory cells
2 Between 1 and 3
3 Moderate thickening of walls without obvious damage to lung architecture
4 Between 3 and 5
5 Increased fibrosis with definite damage to lung structure and formation of fibrous bands or small fibrous masses
6 Between 5 and 7
7 Severe distortion of structure and large fibrous areas; Typical silica nodules formed by collagen fibers.
8 Total fibrous obliteration of the field