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Table 1 Association (Odds Ratios and 95% Confidence Intervals) between Red Meat Intake and Colorectal Cancer according to Inferred NAT2 phenotype in two pooled analyses

From: The role of heterocyclic aromatic amines in colorectal cancer: the evidence from epidemiologic studies

   

Red Meat Intake

 

Population

NAT2

Case/Controls

Quartile 1

Quartile 2

Quartile 3

Quartile 4

Ptrend

White [34]

S

4906/5488

1.0

1.15

1.03–1.28

1.30

1.17–1.46

1.43

1.28–1.61

NA

R/I

3384/3627

1.0

1.15

1.11–1.46

1.27

1.11–1.46

1.38

1.20–1.59

NA

  

Pinteraction = 0.97

 

Japanese + African Americans [35]

S

295/1057

1.0

1.28

0.84–1.93

1.04

0.69–1.58

0.92

0.60–1.40

0.53

I

1288/4829

1.0

1.30

1.06–1.59

1.17

0.96–1.43

1.35

1.10–1.65

0.01

R

1069/2206

1.0

1.21

0.96–1.51

1.16

0.92–1.45

1.47

1.17–1.86

0.003

  

Pinteraction = 0.03

 
  1. NAT2 phenotype: S = Slow; I=Intermediate; R = Rapid.