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Fig. 11 | Genes and Environment

Fig. 11

From: Metabolism and biomarkers of heterocyclic aromatic amines in humans

Fig. 11

Co-oxidation of HbO2 by N-hydroxylated aromatic amines and HAAs in human RBCs and met-Hb formation. The mass spectrum of the AαC sulfinamide formed at the β-Cys93 of Hb was acquired by ion trap mass spectrometry employing electrospray ionization in the positive ion mode. The AαC-modified Hb was digested with Glu-C, and the peptide sequence encompassing the AαC sulfinamide adduct formed at Hb β-Cys93 is reported. Adapted with permission from [226]

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