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Table 4 Multivariate poisson regression analysis for association between genetic polymorphism (MTHFR) and chromosomal damage in BD-exposed workers

From: Folate metabolism modifies chromosomal damage induced by 1,3-butadiene: results from a match-up study in China and in vitro experiments

Name Β 95%CI X2 P FR
   low Upper    
Intercept 1.6065 0.8771 2.3360 18.63 <.0001  
Gender (female) 0.3131 −0.2650 0.8911 1.13 0.2884 1.37 (0.77–2.44)
Age(≤40) 0.1725 −0.3341 0.6790 0.45 0.5046 1.19 (0.72–1.97)
OL(≤20) −0.2213 −0.7090 0.2663 0.79 0.3736 0.80 (0.49–1.31)
Smoking (no) −0.1197 − 0.6219 0.3826 0.22 0.6405 0.89 (0.54–1.47)
Drinking (no) −0.2699 − 0.7513 0.2116 1.21 0.2720 0.76 (0.47–1.24)
MTHFR677(CC) −1.0185 −1.6335 −0.4036 10.54 0.0012 0.36 (0.20–0.67)*
MTHFR677(CT) −0.7055 −1.1513 −0.2597 9.62 0.0019 0.49 (0.32–0.77)*
MTHFR1298(AC/CC) 0.2778 −0.1801 0.7357 1.41 0.2344 1.32 (0.84–2.09)
  1. *Compared in BD-exposed group, MTHFR 677 TT genotype as reference, P < 0.05. OL: Occupational Longevity